Uranium in PDB 2veo: X-Ray Structure of Candida Antarctica Lipase A in Its Closed State.

All present enzymatic activity of X-Ray Structure of Candida Antarctica Lipase A in Its Closed State.:
3.1.1.3;

The structure of X-Ray Structure of Candida Antarctica Lipase A in Its Closed State., PDB code: 2veo was solved by D.J.Ericsson, A.Kasrayan, P.Johansson, T.Bergfors, A.G.Sandstrom, J.E.Backvall, S.L.Mowbray, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.20
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	91.539, 91.539, 299.842, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 22.1

The binding sites of Uranium atom in the X-Ray Structure of Candida Antarctica Lipase A in Its Closed State. (pdb code 2veo). This binding sites where shown within 5.0 Angstroms radius around Uranium atom.
In total 4 binding sites of Uranium where determined in the X-Ray Structure of Candida Antarctica Lipase A in Its Closed State., PDB code: 2veo:
Jump to Uranium binding site number: 1; 2; 3; 4;

Uranium binding site 1 out of 4 in the X-Ray Structure of Candida Antarctica Lipase A in Its Closed State.


Mono view


Stereo pair view

A full contact list of Uranium with other atoms in the U binding site number 1 of X-Ray Structure of Candida Antarctica Lipase A in Its Closed State. within 5.0Å range: probe atom residue distance (Å) B Occ A:U1441 b:23.1 occ:0.20 OD2 A:ASP292 2.1 33.6 1.0 OE1 A:GLU298 2.8 30.9 1.0 OE2 A:GLU298 3.0 31.1 1.0 CD A:GLU298 3.1 30.3 1.0 CG A:ASP292 3.4 33.0 1.0 NE A:ARG255 4.2 25.5 1.0 OD1 A:ASP292 4.2 33.5 1.0 CB A:ASP292 4.2 32.5 1.0 CG A:GLU298 4.4 29.0 1.0 NH2 A:ARG255 4.8 26.1 1.0 CZ A:PHE251 4.9 21.3 1.0 CZ A:ARG255 5.0 26.1 1.0

Uranium binding site 2 out of 4 in the X-Ray Structure of Candida Antarctica Lipase A in Its Closed State.


Mono view


Stereo pair view

A full contact list of Uranium with other atoms in the U binding site number 2 of X-Ray Structure of Candida Antarctica Lipase A in Its Closed State. within 5.0Å range: probe atom residue distance (Å) B Occ A:U1442 b:26.9 occ:0.20 OE2 A:GLU314 2.2 19.6 1.0 OD2 A:ASP220 2.5 16.4 1.0 CD A:GLU314 3.3 18.9 1.0 CG A:ASP220 3.4 15.5 1.0 OD1 A:ASP220 3.7 16.5 1.0 CG A:GLU314 4.0 17.3 1.0 OE1 A:GLU314 4.3 19.4 1.0 CB A:ASP220 4.7 14.4 1.0 CG1 A:VAL311 4.8 13.4 1.0 CG A:PRO341 5.0 9.2 1.0 CB A:PRO341 5.0 9.2 1.0

Uranium binding site 3 out of 4 in the X-Ray Structure of Candida Antarctica Lipase A in Its Closed State.


Mono view


Stereo pair view

A full contact list of Uranium with other atoms in the U binding site number 3 of X-Ray Structure of Candida Antarctica Lipase A in Its Closed State. within 5.0Å range: probe atom residue distance (Å) B Occ B:U1441 b:31.1 occ:0.20 OD2 B:ASP292 2.1 34.3 1.0 OE1 B:GLU298 2.4 32.4 1.0 OE2 B:GLU298 3.0 32.6 1.0 CD B:GLU298 3.1 32.2 1.0 CG B:ASP292 3.3 34.0 1.0 OD1 B:ASP292 4.0 34.3 1.0 CB B:ASP292 4.2 33.6 1.0 NE B:ARG255 4.4 30.0 1.0 CG B:GLU298 4.5 31.2 1.0 NH2 B:ARG255 4.9 30.3 1.0 CZ B:PHE251 5.0 27.9 1.0

Uranium binding site 4 out of 4 in the X-Ray Structure of Candida Antarctica Lipase A in Its Closed State.


Mono view


Stereo pair view

A full contact list of Uranium with other atoms in the U binding site number 4 of X-Ray Structure of Candida Antarctica Lipase A in Its Closed State. within 5.0Å range: probe atom residue distance (Å) B Occ B:U1442 b:23.9 occ:0.20 OE2 B:GLU314 2.4 20.8 1.0 OD2 B:ASP220 2.4 17.6 1.0 CG B:ASP220 3.2 16.5 1.0 OD1 B:ASP220 3.3 17.1 1.0 CD B:GLU314 3.5 19.7 1.0 CG B:GLU314 4.1 19.4 1.0 OE1 B:GLU314 4.4 20.8 1.0 CB B:ASP220 4.6 15.9 1.0 CG B:PRO341 4.9 11.2 1.0 CB B:PRO341 5.0 11.4 1.0

D.J.Ericsson, A.Kasrayan, P.Johansson, T.Bergfors, A.G.Sandstrom, J.E.Backvall, S.L.Mowbray. X-Ray Structure of Candida Antarctica Lipase A Shows A Novel Lid Structure and A Likely Mode of Interfacial Activation. J.Mol.Biol. V. 376 109 2008.
ISSN: ISSN 0022-2836
PubMed: 18155238
DOI: 10.1016/J.JMB.2007.10.079